SPINMS.CA | MS Injection Sites
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MS Injection Sites

MS Injection Sites

Where and how you inject your MS therapy will depend on the type of disease-modifying drug (DMD) your neurologist has prescribed for you.


If you have been prescribed Rebif® (interferon beta-1a), Betaseron® (interferon beta-1b), Extavia® (interferon beta-1b), or Copaxone® (glatiramer acetate), the drug is administered by subcutaneous injection (just under the skin). If you have been prescribed Avonex® (interferon beta-1a), the drug is administered by intramuscular injection (into the muscle).

Please consult with your MS nurse before you start your injections. You and your nurse can determine which injections sites are most suitable for you.


Tips for subcutaneous and intramuscular injections

The following recommendations apply to selecting an injection site for both subcutaneous and intramuscular injections:

  1. Avoid frequent injections into the same area by rotating injection sites to keep the skin healthy. Develop a pattern for injections by alternating between the left and right sides of your body.
  2. When you go back to the general area where you have previously injected, choose a new site at least 1 to 1.5 inches from the last injection site.
  3. Avoid injecting in areas with bruises, tenderness, or irritation from prior injections.
  4. Always clean the skin of your injection site as recommended by your nurse.
  5. Always follow the storage and preparation guidelines for your medication as noted in the information booklet.

Subcutaneous injection sites


The blue areas on the diagram are the most effective areas on your body to administer an injection because there is a fatty layer of tissue just under the skin.

Subcutaneus Injection sites


Intramuscular Injection sites